Invitrogen

beta-1,2 Adaptin Monoclonal Antibody (100/1)

Name: beta-1,2 Adaptin Monoclonal Antibody (100\/1)
Brand: Invitrogen
SKU: MA1-25065

2 篇参考文献

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image beta-1,2 Adaptin Monoclonal Antibody (100/1)

产品信息

MA1-25065

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫细胞化学 (ICC/IF)

1:250

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免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Bovine, Human, Rat

已发表种属

Bovine, C. elegans

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

100/1

抗原

AP-2 adaptor protein from bovine brain.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

Ascites

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2058203

产品详细信息

Recommended positive controls: rat brain, MDCK.

This antibody stains clathrin-coated membranes at the plasma membrane, and in the Golgi region of methanol-fixed MDBK cells. By Western blot on bovine and rat brain preparations, this antibody detects a major band of AP-1 at ~115 kDa and a minor component at ~110 kDa, and bands at ~104 and ~112 kDa representing AP2. The antibody reacts with polypeptides at ~100 kDa in bovine liver, human heart fibroblasts and MDBK cells, but not with any components in the 110-115 kDa range from these sources, or from rat PC12 cells, neuroblastoma or astrocytes.

靶标信息

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: adapter-related protein complex 1 subunit beta-1; adapter-related protein complex 2 beta subunit; adapter-related protein complex 2 subunit beta; adaptin, beta 2 (beta); Adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; Adaptor protein complex AP-2 subunit beta; adaptor related protein complex 1 beta 1 subunit; adaptor related protein complex 2, beta 1 subunit; adaptor-related protein complex 1 beta 1 subunit; Adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; Adaptor-related protein complex 2 subunit beta; adaptor-related protein complex 2, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; AP-1 complex subunit beta-1; AP-2 complex subunit beta; AP105B; beta adaptin; Beta-1-adaptin; Beta-2-adaptin; Beta-adaptin; Beta-adaptin 1; beta-prime-adaptin; beta1-adaptin; beta2-adaptin; Clathrin assembly protein complex 1 beta large chain; Clathrin assembly protein complex 2 beta large chain; clathrin-associated / assembly / adaptor protein, large, beta 1; clathrin-associated/assembly/adaptor protein, large, beta 1; Golgi adaptor HA1/AP1 adaptin beta subunit; Plasma membrane adaptor HA2/AP2 adaptin beta subunit; plasma membrane adaptor HA2/AP2 adaptor beta subunit; testicular tissue protein Li 22

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基因别名: ADTB1; ADTB2; AP105A; AP105B; AP1B1; AP2-BETA; AP2B1; BAM22; CLAPB1; CLAPB2