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OPA1-15267 detects the beta-2 adrenergic receptors from human samples.
OPA1-15267 has been successfully used in immunohistochemistry procedures. By immunohistochemistry, OPA1-15267 detects the beta-2 adrenergic receptors in formalin fixed, paraffin embedded human tissues.
The OPA1-15267 immunogen is a synthetic peptide (KLH conjugated) corresponding to the C-terminus.
Store at 4°C short term. For extended storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。