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Invitrogen
beta-Defensin 1 Polyclonal Antibody
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beta-Defensin 1 Antibody (PA5-75666) in WB
Western blot analysis of beta-Defensin 1 in Lane 1: HEK293T whole cell lysate, Lane 2: mouse liver tissue lysate, Lane 3: rat heart tissue lysate. Samples were incubated with beta-Defensin 1 polyclonal antibody (Product # PA5-75666) at a dilution of 1:500.
产品信息
PA5-75666
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human beta-Defensin 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1; rBD-1
基因别名: AW260221; BD-1; BD1; DEFB-1; DEFB1; DEFB101; HBD1
UniProt ID: (Human) P60022, (Rat) O89117, (Mouse) P56386
Entrez Gene ID: (Human) 1672, (Rat) 83687, (Mouse) 13214
innate immune response in mucosa
acute inflammatory response
chemotaxis
immune response
G-protein coupled receptor signaling pathway
response to bacterium
antibacterial humoral response
cAMP-mediated signaling
response to testosterone
calcium-mediated signaling using intracellular calcium source
defense response to bacterium
innate immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of sperm motility involved in capacitation
defense response
