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Invitrogen
hnRNP LL Polyclonal Antibody
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hnRNP LL Antibody (PA5-87841) in WB
Western blot analysis of hnRNP LL in extracts of various cell lines. Samples were incubated with hnRNP LL Polyclonal antibody (Product # PA5-87841) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87841
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human HNRPLL (NP_6124032)
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IRNDNDSWDY TKPYLGRRDR GKGRQRQAIL GEHPSSFRHD GYGSHGPLLP LPSRYRMGSR DTPELVAYPL PQASSSYMHG GNPSGSVVMV SGLHQLKMNC S; Positive Samples: A-549, DU145, HepG2, 293T, Mouse liver
靶标信息
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Heterogeneous nuclear ribonucleoprotein L-like; hnRNPLL; stromal RNA regulating factor; Stromal RNA-regulating factor
基因别名: 2510028H02Rik; 2810036L13Rik; AI256697; AI852082; BLOCK24; HNRNPLL; HNRPLL; SRRF
UniProt ID: (Human) Q8WVV9, (Mouse) Q921F4
Entrez Gene ID: (Human) 92906, (Mouse) 72692
