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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RLFLFPGESAQ NEATSYHQK
Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: membrane progesterone P4 receptor gamma; membrane progesterone receptor gamma; mPR gamma; progesterone and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; unnamed protein product
基因别名: MPRG
UniProt ID: (Human) Q9NXK6
Entrez Gene ID: (Human) 54852