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Progen
nup153 Monoclonal Antibody (nup7A8)
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产品信息
651141
产品规格
种属反应
Human,
Marsupial,
Mouse,
Rat,
Xenopus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
nup7A8
抗原
Nuclear Matrix Protein Fraction Prepared From Rat Liver Nuclei
偶联物
形式
Liquid
浓度
Conc. Not Determined
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Recognizes the nuclear pore complex (NPC) protein nup153 (190 kD), present on the inner aspect of NPC with attached filament bundles. It is also reactive with the soluble form of nup153 found e.g. during meiotic metaphase. Epitope in rat liver was mapped to N-terminal domain.
靶标信息
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 153 kDa nucleoporin; nuclear pore complex protein hnup153; Nuclear pore complex protein Nup153; nucleoporin 153kD; nucleoporin 153kDa; Nucleoporin Nup153; nucleoporin Nup153 homolog
基因别名: B130015D15Rik; C88147; HNUP153; N153; NUCZINK; NUP153; XELAEV_18031694mg
UniProt ID: (Human) P49790, (Xenopus) Q640Z6
Entrez Gene ID: (Human) 9972, (Rat) 25281, (Mouse) 218210, (Xenopus) 398374
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear division
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
viral entry into host cell
negative regulation of RNA export from nucleus
nuclear pore complex assembly
viral penetration into host nucleus
intracellular transport of virus
regulation of cellular response to heat
nucleocytoplasmic transport
protein transport
mRNA transport
transmembrane transport
