Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
pro-Collagen II Monoclonal Antibody (819447)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
MA5-61330
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
819447
抗原
Chinese hamster ovary cell line CHO-derived recombinant human Pro-Collagen II, Gln26-Arg266 and Gly957-Leu1487
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Pro-collagen II is the precursor form of collagen type II, an essential structural protein predominantly found in cartilage. It is synthesized by chondrocytes and undergoes post-translational modifications before being secreted into the extracellular matrix, where it is processed into mature collagen fibers. These fibers provide tensile strength and elasticity to cartilaginous tissues, playing a critical role in maintaining the integrity and function of joints. Mutations or defects in the gene encoding pro-collagen II can lead to a range of skeletal disorders, such as osteoarthritis, achondrogenesis, and spondyloepiphyseal dysplasia. Given its fundamental role in cartilage structure and function, pro-collagen II is a significant focus in research related to cartilage repair, regenerative medicine, and the treatment of degenerative joint diseases. Understanding the synthesis, processing, and regulation of pro-collagen II is crucial for developing therapeutic strategies aimed at mitigating cartilage-related pathologies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
