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Invitrogen
proCNP Polyclonal Antibody
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产品信息
PA5-57241
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PKVPRTPPAE ELAEPQAAGG GQKKGDKAPG GGGANLKGDR SRLLRDLRVD TKSRAAWARL LQEHPNARKY KGANKKGLSK GCFGLKLDRI GSMSGLGC
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
靶标信息
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type natriuretic peptide; natriuretic peptide precursor type C
基因别名: CNP; CNP2; NPPC
UniProt ID: (Human) P23582
Entrez Gene ID: (Human) 4880
ossification
response to hypoxia
growth plate cartilage chondrocyte differentiation
growth plate cartilage chondrocyte proliferation
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
negative regulation of cell proliferation
post-embryonic development
regulation of cAMP metabolic process
regulation of cGMP metabolic process
positive regulation of cGMP biosynthetic process
regulation of multicellular organism growth
response to drug
single organism reproductive process
response to ethanol
positive regulation of osteoblast differentiation
positive regulation of vasodilation
regulation of smooth muscle cell proliferation
negative regulation of DNA metabolic process
negative regulation of meiotic cell cycle
negative regulation of oocyte maturation
regulation of cardiac conduction
