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Invitrogen
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Human Brevican quantitates human Brevican in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Brevican.
Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BCAN, BEHAB, CSPG7, UNQ2525/PRO6018
基因ID : (Human) 63827
基因符号 : BCAN
蛋白别名 : BEHAB, Brain-enriched hyaluronan-binding protein, Brevican core protein, Chondroitin sulfate proteoglycan 7, chondroitin sulfate proteoglycan BEHAB
UniProt ID (Human) Q96GW7