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Human CD177 quantitates human CD177 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD177.
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : HNA-2, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1
基因ID : (Human) 57126
基因符号 : CD177
蛋白别名 : cell surface receptor, human neutrophil alloantigen 2a, human neutrophil antigen 2, NB1 glycoprotein, polycythemia rubra vera protein 1, unnamed protein product
UniProt ID (Human) Q8N6Q3