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Human CD46 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human CD46 in serum, plasma, and cell culture supernatants.
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : AHUS2, MCP, MIC10, TLX, TRA2.10
基因ID : (Human) 4179
基因符号 : CD46
蛋白别名 : antigen identified by monoclonal antibody TRA-2-10, CD46 antigen, complement regulatory protein, CD46 molecule, complement membrane cofactor protein, measles virus receptor, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MGC26544, trophoblast leucocyte common antigen, trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen, unnamed protein product
UniProt ID (Human) P15529