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Invitrogen
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Human Chitotriosidase quantitates human Chitotriosidase in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Chitotriosidase.
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CHI3, CHIT, CHITD
基因ID : (Human) 1118
基因符号 : CHIT1
蛋白别名 : chitinase 1 (chitotriosidase), Chitotriosidase, EC 3.2.1.14, FLJ00314, MGC125322, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase, unnamed protein product
UniProt ID (Human) Q13231