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Human CytokeRatin 8/KRT8 quantitates human Cytokeratin 8/KRT8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cytokeratin 8/KRT8.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
基因ID : (Human) 3856
基因符号 : KRT8
蛋白别名 : cytokeratin 8, cytokeratin-8, keratin 8, type II, type-II keratin Kb8, unnamed protein product
UniProt ID (Human) P05787