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Human Desmoglein-2 quantitates human Desmoglein-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Desmoglein-2.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CDHF5, HDGC
基因ID : (Human) 1829
基因符号 : DSG2
蛋白别名 : ARVC10, ARVD10, CMD1BB, DSG-2, MGC117034, MGC117036, MGC117037, cadherin family member 5
UniProt ID (Human) Q14126