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Human GPR56 quantitates human GPR56 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GPR56.
GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : BFPP, BPPR, CDCBM14B, CDCBM15A, GPR56, TM7LN4, TM7XN1
基因ID : (Human) 9289
基因符号 : ADGRG1
蛋白别名 : 7-transmembrane protein with no EGF-like N-terminal domains-1, Cyt28, DKFZp781L1398, G protein-coupled receptor 56, SLR32, testicular tissue protein Li 77, unnamed protein product
UniProt ID (Human) Q9Y653