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Human IL-16 quantitates human IL-16 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-16.
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : LCF, NIL16, prIL-16, PRIL16
基因ID : (Human) 3603
基因符号 : IL16
蛋白别名 : CD8+ T cell-derived cytokine, il 16, ILN, Interleukin, Interleukin16, M-IL-16, FLJ16806, FLJ42735, FLJ44234, H-IL-16, lymphocyte chemoattractant factor, neuronal interleukin 16, neuronal pro-IL-16, prointerleukin 16, putative interleukin-16 precursor, unnamed protein product
UniProt ID (Human) Q14005