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Human L1CAM quantitates human L1CAM in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human L1CAM.
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CAML1, CD171, HSAS, HSAS1, HYCX, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
基因ID : (Human) 3897
基因符号 : L1CAM
蛋白别名 : antigen identified by monoclonal antibody R1, CD 171, CD171 molecule, sCD171, sL1 CAM, sL1CAM, soluble CD 171, soluble CD171, soluble L1 CAM, soluble L1CAM, IgG super gene family, unnamed protein product
UniProt ID (Human) P32004