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Human NOV ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human NOV in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay human NOV in approximately 1,000 ELISA plate wells.
This PeproTech ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant proteins in a sandwich ELISA format. This ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells. The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
NOV is a member of the CCN family of secreted, cysteine-rich regulatory proteins. The full-length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorigenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell-surface integrins, and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CCN3, IBP-9, IGFBP-9, IGFBP9, NOV, NOVH
基因ID : (Human) 4856
基因符号 : CCN3
蛋白别名 : CCN family member 3, Cellular communication network factor 3, IBP-9, IGF-binding protein 9, Insulin-like growth factor-binding protein 9, Nephro blastoma-overexpressed gene protein homolog, nephroblastoma overexpressed, nephroblastoma-overexpressed gene protein homolog, NOV, NovH, Protein NOV homolog, unnamed protein product
UniProt ID (Human) P48745