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Human PADI4 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human PADI4 in serum, plasma, and cell culture supernatants.
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : PAD, PAD4, PADI4, PADI5, PDI4, PDI5
基因ID : (Human) 23569
基因符号 : PADI4
蛋白别名 : HL-60 PAD, PADI-H protein, peptidyl arginine deiminase, type IV, type V, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, Protein-arginine deiminase type-4
UniProt ID (Human) Q9UM07