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Human Ret quantitates human Ret in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Ret.
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. RET transduce signals for cell growth and differentiation. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
基因ID : (Human) 5979
基因符号 : RET
蛋白别名 : cadherin family member 12, Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), EC 2.7.10.1, ELKS, Hydroxyaryl protein kinase, kinase Ret, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, OTTHUMP00000216967, RET ELE1, cadherin-related family member 16, proto-oncogene c-Ret, rearranged during transfection, ret, ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease), RET receptor tyrosine kinase, unnamed protein product
UniProt ID (Human) P07949