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Invitrogen
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Human SGK1 quantitates human SGK1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SGK1.
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : SGK
基因ID : (Human) 6446
基因符号 : SGK1
蛋白别名 : N-terminal variant of classic Sgk1, serine/threonine protein kinase SGK, Sgk1_i2, unnamed protein product
UniProt ID (Human) O00141