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Human TrkA quantitates human TrkA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TrkA.
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA
基因ID : (Human) 4914
基因符号 : NTRK1
蛋白别名 : DKFZp781I14186, EC 2.7.10.1, kinase TrkA, gp140trk, neurotrophic tyrosine kinase, receptor, type 1, Oncogene TRK, trk tyrosine-specific protein kinase, TRK1-transforming tyrosine kinase protein, tropomyosin receptor kinase A, tropomyosin-related kinase A, tyrosine kinase receptor A, unnamed protein product
UniProt ID (Human) P04629