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Mouse B7-H3 (CD276) ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of mouse B7-H3 in serum, plasma, and cell culture supernatants.
CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : 6030411F23Rik, B7-H3, B7h3, B7RP-2
基因ID : (Mouse) 102657
基因符号 : Cd276
蛋白别名 : B7 homolog 3, costimulatory molecule, Ig protein, sB7 H3, sB7H3, sCD276, soluble B7 H3, soluble B7H3, soluble CD276, unnamed protein product
UniProt ID (Mouse) Q8VE98