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Rat 4-1BB/TNFRSF9/CD137 quantitates rat 4-1BB/TNFRSF9/CD137 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat 4-1BB/TNFRSF9/CD137.
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : 4-1BB
基因ID : (Rat) 500590
基因符号 : Tnfrsf9
蛋白别名 : 4 1 BB, 41BB, s4 1 BB, s4 1BB, s41BB, sCD137, soluble 4 1 BB, soluble 4 1BB, soluble 41BB, soluble CD137, tumor necrosis factor receptor superfamily member 9