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MSACL 2025
Tradeshow
Sep 21, 2025
- Sep 26, 2025
Hotel Bonaventure Montréal | 900 Rue De la Gauchetière O, Montréal, QC H5A 1E4, Canada
Join Thermo Fisher Scientific at MSACL 2025 to explore the latest in clinical research applications and mass spectrometry innovations! Our experienced team of experts will be available to answer your questions and discuss the latest product advancements to address your real-world health questions.
2025 Workshops
Register now for our workshops featuring industry experts.
New Frontiers in LC-MS – developing an efficient discovery to validation pipeline
Tuesday, September 23 | 12:45 - 2 p.m. EDT
Significant efforts have been dedicated towards discovering, developing, and validating biomarkers for disease diagnosis, prognosis, and therapy guidance. Achieving these goals requires laboratories to produce reproducible results through streamlined workflows and the adoption of innovative technologies. However, the complexity of study designs, labor-intensive sample preparation, and the intricacies of LC-MS workflows have limited the number of robust validation studies for newly identified biomarkers.
In this workshop, our first speaker will discuss real-world analysis of neurodegenerative disease pathology markers (i.e.: ALS biomarkers) from extracellular vesicles (EVs) and the utilization of novel, breakthrough mass spectrometry technologies driving robust biomarker identification and translation towards clinical settings. Our second workshop speaker will present a high-throughput quantitative proteomics workflow, highlighting practical guidelines and efficiencies across the workflow towards clinical-grade biomarker candidates.
Speakers: Patrick Vanderboom, Ph.D., Mayo Clinic & Qin Fu, Ph.D., Thermo Fisher Scientific
Promising applications of Clinical LC-MS – A review of existing and new QQQ technologies to advance free testosterone measurement accurately and reliably
Thursday, September 25 | 7:30 - 9 a.m. EDT
Accurate assessment of free testosterone (FT) is essential in evaluating androgen status, particularly in cases where total testosterone may be misleading due to altered binding protein levels. This workshop will describe a practical and state-of-the-art LC-MS/MS method for directly measuring FT from dialysate using equilibrium dialysis (ED), offering a streamlined and efficient solution for clinical laboratories.
Presenters will also introduce a new high-end triple quadrupole from Thermo Fisher and discuss how the newest hardware and software features enabled on the system deliver enhanced performance, increased system robustness, and improved productivity to meet demands of the high-volume clinical research and applied markets.
Speakers: Jessica Colon-Franco, Ph.D., Cleveland Clinic; Leslie Farris, Ph.D., Cleveland Clinic; Kerry Hassell, Ph.D., Thermo Fisher Scientific
Posters
| Date and time | Poster No. | Title |
|---|---|---|
Wed, Sep 24 | #32a | |
Wed, Sep 24 | #25a | |
Wed, Sep 24 | #22a | |
Wed, Sep 24 | #14a | Detection and quantification of GLP-1 analogs in human plasma: A comprehensive analytical approach |
Wed, Sep 24 | #1a | Smart solutions for high analyte concentrations and carryover in LC-MS monitoring |
Wed, Sep 24 | #18a | Deciphering Spatial Variation in Lipid Profiles of X-Ray Irradiated Cells Using nLC and Orbitrap 240 MS |
Wed, Sep 24 | #41b | |
Wed, Sep 24 | #31b | |
Thu, Sep 25 | #12c | Evaluation of prioritized peptide acquisition for multiplexed single-cell proteomics on an Thermo Scientific Orbitrap Astral Zoom mass spectrometer |
Thu, Sep 25 | #30c | Using the New Thermo Scientific Stellar mass spectrometer to confirm and quantify 31 drugs of abuse, including THC, in oral fluid |
Thu, Sep 25 | #18d |
Featured products
Thermo Scientific Tox Explorer Collection
The Thermo Scientific Tox Explorer Collection is an all-in-one LC-MS/MS solution that provides confident answers to scientists in forensic toxicology, clinical research toxicology, employee drug testing, and sports anti-doping. It is now available in HRAM and QQQ MS platforms.
Thermo Scientific Orbitrap Exploris 120 mass spectrometer
The Thermo Scientific Orbitrap Exploris 120 mass spectrometer sets the new standard in instrument productivity and ruggedness, delivering high confidence results for a broad range of toxicology compounds.
Thermo Scientific VeriSpray PaperSpray ion source
Improve turnaround time, reduce cost per test and minimize sample preparation with the Thermo Scientific VeriSpray PaperSpray ion source, a fully automated, high-throughput, direct ionization technique used with our newest Thermo Scientific TSQ triple quadrupole mass spectrometers.
Thermo Scientific TSQ Altis Plus mass spectrometer
With superior acquisition speeds, enhanced sensitivity, and exceptional robustness, the TSQ Altis Plus mass spectrometer delivers accuracy and precision for low-level compound detection and quantitation in complex matrices.
Orbitrap Astral mass spectrometer
The Thermo Scientific Orbitrap Astral Mass Spectrometer combines three mass analyzers: a quadrupole mass analyzer for high selectivity and high ion transmission, an Orbitrap mass analyzer for high dynamic range and high resolution measurements, and the novel Astral analyzer for fast and sensitive measurements. By combining these three mass analyzers and orchestrating the coordination of 5 separate ion packets within the instrument in parallel a new standard for mass spectrometry performance is achieved to unlock new insights into biology and disease mechanisms.
2025 Workshops
Register now for our workshops featuring industry experts.
New Frontiers in LC-MS – developing an efficient discovery to validation pipeline
Tuesday, September 23 | 12:45 - 2 p.m. EDT
Significant efforts have been dedicated towards discovering, developing, and validating biomarkers for disease diagnosis, prognosis, and therapy guidance. Achieving these goals requires laboratories to produce reproducible results through streamlined workflows and the adoption of innovative technologies. However, the complexity of study designs, labor-intensive sample preparation, and the intricacies of LC-MS workflows have limited the number of robust validation studies for newly identified biomarkers.
In this workshop, our first speaker will discuss real-world analysis of neurodegenerative disease pathology markers (i.e.: ALS biomarkers) from extracellular vesicles (EVs) and the utilization of novel, breakthrough mass spectrometry technologies driving robust biomarker identification and translation towards clinical settings. Our second workshop speaker will present a high-throughput quantitative proteomics workflow, highlighting practical guidelines and efficiencies across the workflow towards clinical-grade biomarker candidates.
Speakers: Patrick Vanderboom, Ph.D., Mayo Clinic & Qin Fu, Ph.D., Thermo Fisher Scientific
Promising applications of Clinical LC-MS – A review of existing and new QQQ technologies to advance free testosterone measurement accurately and reliably
Thursday, September 25 | 7:30 - 9 a.m. EDT
Accurate assessment of free testosterone (FT) is essential in evaluating androgen status, particularly in cases where total testosterone may be misleading due to altered binding protein levels. This workshop will describe a practical and state-of-the-art LC-MS/MS method for directly measuring FT from dialysate using equilibrium dialysis (ED), offering a streamlined and efficient solution for clinical laboratories.
Presenters will also introduce a new high-end triple quadrupole from Thermo Fisher and discuss how the newest hardware and software features enabled on the system deliver enhanced performance, increased system robustness, and improved productivity to meet demands of the high-volume clinical research and applied markets.
Speakers: Jessica Colon-Franco, Ph.D., Cleveland Clinic; Leslie Farris, Ph.D., Cleveland Clinic; Kerry Hassell, Ph.D., Thermo Fisher Scientific
Posters
| Date and time | Poster No. | Title |
|---|---|---|
Wed, Sep 24 | #32a | |
Wed, Sep 24 | #25a | |
Wed, Sep 24 | #22a | |
Wed, Sep 24 | #14a | Detection and quantification of GLP-1 analogs in human plasma: A comprehensive analytical approach |
Wed, Sep 24 | #1a | Smart solutions for high analyte concentrations and carryover in LC-MS monitoring |
Wed, Sep 24 | #18a | Deciphering Spatial Variation in Lipid Profiles of X-Ray Irradiated Cells Using nLC and Orbitrap 240 MS |
Wed, Sep 24 | #41b | |
Wed, Sep 24 | #31b | |
Thu, Sep 25 | #12c | Evaluation of prioritized peptide acquisition for multiplexed single-cell proteomics on an Thermo Scientific Orbitrap Astral Zoom mass spectrometer |
Thu, Sep 25 | #30c | Using the New Thermo Scientific Stellar mass spectrometer to confirm and quantify 31 drugs of abuse, including THC, in oral fluid |
Thu, Sep 25 | #18d |
Featured products
Thermo Scientific Tox Explorer Collection
The Thermo Scientific Tox Explorer Collection is an all-in-one LC-MS/MS solution that provides confident answers to scientists in forensic toxicology, clinical research toxicology, employee drug testing, and sports anti-doping. It is now available in HRAM and QQQ MS platforms.
Thermo Scientific Orbitrap Exploris 120 mass spectrometer
The Thermo Scientific Orbitrap Exploris 120 mass spectrometer sets the new standard in instrument productivity and ruggedness, delivering high confidence results for a broad range of toxicology compounds.
Thermo Scientific VeriSpray PaperSpray ion source
Improve turnaround time, reduce cost per test and minimize sample preparation with the Thermo Scientific VeriSpray PaperSpray ion source, a fully automated, high-throughput, direct ionization technique used with our newest Thermo Scientific TSQ triple quadrupole mass spectrometers.
Thermo Scientific TSQ Altis Plus mass spectrometer
With superior acquisition speeds, enhanced sensitivity, and exceptional robustness, the TSQ Altis Plus mass spectrometer delivers accuracy and precision for low-level compound detection and quantitation in complex matrices.
Orbitrap Astral mass spectrometer
The Thermo Scientific Orbitrap Astral Mass Spectrometer combines three mass analyzers: a quadrupole mass analyzer for high selectivity and high ion transmission, an Orbitrap mass analyzer for high dynamic range and high resolution measurements, and the novel Astral analyzer for fast and sensitive measurements. By combining these three mass analyzers and orchestrating the coordination of 5 separate ion packets within the instrument in parallel a new standard for mass spectrometry performance is achieved to unlock new insights into biology and disease mechanisms.
2024 Breakfast workshops
Practical considerations for standardizing LC-MS assays in clinical labs
This workshop focused on the practical aspects of developing and validating LC-MS assays in clinical labs. Dr. Stefani Thomas and Dr. Tony Maus, renowned experts from esteemed institutions, shared their knowledge and experiences.
An optimized, simplified workflow for the targeted proteomic analysis of fibrinogen in 4,200 plasma samples
Speaker: Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Join Dr. Thomas (UMN) at MSACL 2024: "An optimized, simplified workflow for the targeted proteomic analysis of fibrinogen in 4,200 plasma samples"
FAIMS: The perfect complement to established LC-MS/MS techniques
Speaker: Anthony Maus, B.S, Ph.D., Mayo Clinic
Anthony Maus, B.S., Ph.D., Mayo Clinic
Join Dr. Maus of Mayo Clinic at MSACL 2024: FAIMS enhances clarity, reduces noise, improves agreement, maintains performance, streamlines analysis.
Unlocking the potential for large-cohort proteomic studies with the Orbitrap Astral mass platform
This workshop delved into the groundbreaking capabilities of the Orbitrap Astral Platform and its role in advancing large-cohort proteomics studies. Gained valuable insights from expert speakers Dr. Jenny Van Eyk and Dr. Yue Xuan and explored the potential for groundbreaking research.
Paradigm shift in biomarker translation: an innovative and automated pipeline to generate and select clinical-grade signature peptides during DIA discovery
Speaker: Jennifer Van Eyk, PhD, Cedars-Sinai Heart Institute
Jennifer Van Eyk, Ph.D., Cedars-Sinai Heart Institute
View Thermo Fisher Scientific's webinar from MSACL 2024 on-demand with Dr. Jenny Van Eyk of Cedars Sinai. Discover the new Orbitrap Astral MS platform.
Introducing the Orbitrap Astral mass spectrometer
Speaker: Yue Xuan, Ph.D., MBA, Thermo Fisher Scientific
Yue Xuan, Ph.D., MBA, Thermo Fisher Scientific
Join Thermo Fisher Scientific's MSACL 2024 workshop with speaker Dr. Yue Xuan exploring large-cohort proteomics with the Orbitrap Astral MS platform
Video testimonials
Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Dr. Thomas discusses her work in developing and validating a mass spectrometry-based assay for fibrinogen.
Erin H. Seeley, Ph.D., Director, Mass Spectrometry Imaging Facility Department of Chemistry, University of Texas at Austin
Dr. Seeley explains how the Orbitrap Fusion Lumos Tribrid Mass Spectrometer allows for seamless transitions between electro spray and MALDI analysis.
Timothy J. Garrett, Ph.D., Associate Professor, University of Florida
Dr. Garrett shares how Thermo Fisher Scientific’s technology has enabled his lab to perform reproducible metabolomics and lipidomics analyses.
Posters
Wednesday, March 20 | ||
|---|---|---|
12:15 p.m. | Poster #69a | Enhanced Detection of Hemoglobin Variants by High-Resolution Accurate Mass (HRAM) Mass Spectrometry for Clinical Research |
12:15 p.m. | Poster #73a | Simultaneous detection of respiratory infectious diseases using immunoprecipitation and liquid chromatography-tandem mass spectrometry |
2:30 p.m. | Poster #61b | Unlocking the Potential of Large-Cohort Proteomics Studies With the Orbitrap Astral Mass Platform |
2:30 p.m. | Poster #73b | An in-depth and high throughput plasma proteomics workflow powered by Orbitrap Exploris 480 mass spectrometer using multi nanoparticle-based workflow |
2:30 p.m. | Poster #69b | Quantitation of a Panel of Per- and Polyfluoroalkyl Substances (PFAS) in Biological Matrix |
Thursday, March 21 | ||
|---|---|---|
9:15 a.m. | Poster #70a | Empower the Confidence for Inborn Error of Metabolism Screening: Quantitation of Amino Acids and Acylcarnitines in Dried Blood Spots by Flow Injection – Orbitrap Mass Spectrometer: |
9:15 a.m. | Poster #72a | Unleashing the Power of HT-DIA Acquisition on Orbitrap Exploris 240 – Precise and Accurate Quantitation at 260 SPD |
12:15 9.m. | Poster #72b | Quantitation of an Oral Fluid Drug Panel Including THC Using with High Resolution Accurate-Mass (HRAM) Mass Spectrometry |
2024 Breakfast workshops
Practical considerations for standardizing LC-MS assays in clinical labs
This workshop focused on the practical aspects of developing and validating LC-MS assays in clinical labs. Dr. Stefani Thomas and Dr. Tony Maus, renowned experts from esteemed institutions, shared their knowledge and experiences.
An optimized, simplified workflow for the targeted proteomic analysis of fibrinogen in 4,200 plasma samples
Speaker: Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Join Dr. Thomas (UMN) at MSACL 2024: "An optimized, simplified workflow for the targeted proteomic analysis of fibrinogen in 4,200 plasma samples"
FAIMS: The perfect complement to established LC-MS/MS techniques
Speaker: Anthony Maus, B.S, Ph.D., Mayo Clinic
Anthony Maus, B.S., Ph.D., Mayo Clinic
Join Dr. Maus of Mayo Clinic at MSACL 2024: FAIMS enhances clarity, reduces noise, improves agreement, maintains performance, streamlines analysis.
Unlocking the potential for large-cohort proteomic studies with the Orbitrap Astral mass platform
This workshop delved into the groundbreaking capabilities of the Orbitrap Astral Platform and its role in advancing large-cohort proteomics studies. Gained valuable insights from expert speakers Dr. Jenny Van Eyk and Dr. Yue Xuan and explored the potential for groundbreaking research.
Paradigm shift in biomarker translation: an innovative and automated pipeline to generate and select clinical-grade signature peptides during DIA discovery
Speaker: Jennifer Van Eyk, PhD, Cedars-Sinai Heart Institute
Jennifer Van Eyk, Ph.D., Cedars-Sinai Heart Institute
View Thermo Fisher Scientific's webinar from MSACL 2024 on-demand with Dr. Jenny Van Eyk of Cedars Sinai. Discover the new Orbitrap Astral MS platform.
Introducing the Orbitrap Astral mass spectrometer
Speaker: Yue Xuan, Ph.D., MBA, Thermo Fisher Scientific
Yue Xuan, Ph.D., MBA, Thermo Fisher Scientific
Join Thermo Fisher Scientific's MSACL 2024 workshop with speaker Dr. Yue Xuan exploring large-cohort proteomics with the Orbitrap Astral MS platform
Video testimonials
Stefani Thomas, Ph.D., DABCC, NRCC, University of Minnesota
Dr. Thomas discusses her work in developing and validating a mass spectrometry-based assay for fibrinogen.
Erin H. Seeley, Ph.D., Director, Mass Spectrometry Imaging Facility Department of Chemistry, University of Texas at Austin
Dr. Seeley explains how the Orbitrap Fusion Lumos Tribrid Mass Spectrometer allows for seamless transitions between electro spray and MALDI analysis.
Timothy J. Garrett, Ph.D., Associate Professor, University of Florida
Dr. Garrett shares how Thermo Fisher Scientific’s technology has enabled his lab to perform reproducible metabolomics and lipidomics analyses.
Posters
Wednesday, March 20 | ||
|---|---|---|
12:15 p.m. | Poster #69a | Enhanced Detection of Hemoglobin Variants by High-Resolution Accurate Mass (HRAM) Mass Spectrometry for Clinical Research |
12:15 p.m. | Poster #73a | Simultaneous detection of respiratory infectious diseases using immunoprecipitation and liquid chromatography-tandem mass spectrometry |
2:30 p.m. | Poster #61b | Unlocking the Potential of Large-Cohort Proteomics Studies With the Orbitrap Astral Mass Platform |
2:30 p.m. | Poster #73b | An in-depth and high throughput plasma proteomics workflow powered by Orbitrap Exploris 480 mass spectrometer using multi nanoparticle-based workflow |
2:30 p.m. | Poster #69b | Quantitation of a Panel of Per- and Polyfluoroalkyl Substances (PFAS) in Biological Matrix |
Thursday, March 21 | ||
|---|---|---|
9:15 a.m. | Poster #70a | Empower the Confidence for Inborn Error of Metabolism Screening: Quantitation of Amino Acids and Acylcarnitines in Dried Blood Spots by Flow Injection – Orbitrap Mass Spectrometer: |
9:15 a.m. | Poster #72a | Unleashing the Power of HT-DIA Acquisition on Orbitrap Exploris 240 – Precise and Accurate Quantitation at 260 SPD |
12:15 9.m. | Poster #72b | Quantitation of an Oral Fluid Drug Panel Including THC Using with High Resolution Accurate-Mass (HRAM) Mass Spectrometry |
2023 Breakfast workshops
Promising clinical applications of ICP-MS
Speaker: Jessica Colón-Franco, Ph.D., Cleveland Clinic Foundation
Speaker: Dr. Michael Lutz, Ph.D., Osteolabs GmbH Germany
New frontiers for pathogen detection using LC-MS
Speaker: Ian Lewis, Ph.D., University of Calgary, Alberta
Speaker: Tony Hu, Ph.D., Professor, Tulane University
Video testimonials
Ian Lewis, Ph.D., Associate Professor and Director of the Alberta Centre for Advanced Diagnostics
“We want to build [diagnostic] tools that will have a real impact on people's lives. We’re on the cusp of making one of those contributions, and it wouldn’t be possible without the support of Thermo Fisher Scientific.”
Jessica Colón-Franco, Ph.D., DABCC, Section Head of Clinical Biochemistry and Director of the Special Chemistry Laboratory, Cleveland Clinic
"We’re working on a method [for lead screening] using dried blood spots in tandem with ICP-MS. What inspires me in my job as a clinical chemist is the ability to provide meaningful answers for physicians and patients.”
Michael Lutz, Ph.D., Senior Adviser, Osteolabs, GmbH Germany
“We are developing clinical assays that are relevant in the field of metabolic bone disorders. We have set up ICP-MS methods that are addressing this unmet clinical need, which affects over 1 billion patients in the world.”
Chris Gill, Vancouver Island University
“My research program has been ongoing for over 20 years. Its primary focus is the development of direct mass spectrometry techniques that provide chemical measurement that’s faster, better, cheaper, and in real-time.”
Posters
Clinical Research | |
Clinical Research | Direct quantitation of 77 therapeutic and clinical toxicology drugs in dried blood spots using the fully automated Transcend DSX-1 system |
Clinical Research | High flow LC-MS analysis of plasma digest for protein identification |
2023 Breakfast workshops
Promising clinical applications of ICP-MS
Speaker: Jessica Colón-Franco, Ph.D., Cleveland Clinic Foundation
Speaker: Dr. Michael Lutz, Ph.D., Osteolabs GmbH Germany
New frontiers for pathogen detection using LC-MS
Speaker: Ian Lewis, Ph.D., University of Calgary, Alberta
Speaker: Tony Hu, Ph.D., Professor, Tulane University
Video testimonials
Ian Lewis, Ph.D., Associate Professor and Director of the Alberta Centre for Advanced Diagnostics
“We want to build [diagnostic] tools that will have a real impact on people's lives. We’re on the cusp of making one of those contributions, and it wouldn’t be possible without the support of Thermo Fisher Scientific.”
Jessica Colón-Franco, Ph.D., DABCC, Section Head of Clinical Biochemistry and Director of the Special Chemistry Laboratory, Cleveland Clinic
"We’re working on a method [for lead screening] using dried blood spots in tandem with ICP-MS. What inspires me in my job as a clinical chemist is the ability to provide meaningful answers for physicians and patients.”
Michael Lutz, Ph.D., Senior Adviser, Osteolabs, GmbH Germany
“We are developing clinical assays that are relevant in the field of metabolic bone disorders. We have set up ICP-MS methods that are addressing this unmet clinical need, which affects over 1 billion patients in the world.”
Chris Gill, Vancouver Island University
“My research program has been ongoing for over 20 years. Its primary focus is the development of direct mass spectrometry techniques that provide chemical measurement that’s faster, better, cheaper, and in real-time.”
Posters
Clinical Research | |
Clinical Research | Direct quantitation of 77 therapeutic and clinical toxicology drugs in dried blood spots using the fully automated Transcend DSX-1 system |
Clinical Research | High flow LC-MS analysis of plasma digest for protein identification |
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