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Large-volume fluid management designed for reliability
Handling large volumes of buffers, media, and process liquids shouldn’t slow you down. Traditional reusable systems introduce cleaning, verification burdens, and added risk at every step. Modern operations demand reliable containment, consistent handling, and uncompromised contamination control—with minimal complexity.
3D Productainer™ BPC assemblies are designed for storage and transportation of large volumes of biopharmaceutical solutions from 50 L to 5,000 L. They are sterile and ready to use for an easy and convenient process implementation. Benefit from solutions trusted for robustness and consistency.
Design features that support scalable liquid management
- cGMP-manufactured chamber films: Thermo Scientific Aegis5-14 and ASI 26/77 films are produced in ISO 7 cleanrooms under cGMP conditions with low-extractables materials suitable for bioprocess applications. Our films have demonstrated biocompatibility and low cytotoxicity to support healthy cell growth. Learn more about bioprocessing films.
- Flexible port and drain configurations: Multiple configurations are provided for flexible incorporation in workflow process steps
- Compatibility with in-market drums, totes, and outer plastic containers: Designed to integrate with common rigid support containers, including drums, totes, and outer plastic containers to promote structural stability for safe handling, transport, and scale-up
- Customizable assemblies for workflows: Use the single-use configurator tool to tailor tubing, end fittings, components, LifeASSURE filters and Productainer™ BPCs for seamless integration across all your bioprocessing steps
- Minimized risk of leaks and simplified set up with the Thermo Scientific BioTitan Retention Device, which provides a 360-degree seal
- Off-the-shelf BPCs are also available to facilitate smooth operations, quality, and supply chain
Use 3D Productainers across bioprocessing workflows
Hydration and preparation of buffers and media
Productainers are built for high-volume fluid handling, offering flexible dispensing options that streamline media and buffer preparation at scale.
Chromatography feed and collection steps
Seamlessly integrate Productainers into your workflow—feed bioprocessing liquids directly into chromatography systems and use multiport configurations to efficiently capture and separate fractions.
Bulk drug substance and precursor storage
Built for demanding workflows, Productainers deliver robust, durable performance within closed systems—supporting secure storage across every stage of your process. Advanced film technology facilitates low extractables and leachables, protecting product integrity from start to finish.
Integration with upstream and downstream liquid transfer
Productainers seamlessly connect upstream and downstream operations, enabling efficient liquid transfer across your entire process. With connectors on both ends, they support true closed-system handling for fermentation and diverse bioprocessing applications—boosting efficiency while minimizing contamination risk.
Ordering information
Related resource
Frequently asked questions
Choosing the right Productainer starts with your process. Define your required working volume—from 50 to 5,000 L—then tailor the configuration to match how you fill, transfer, and dispense. Consider top and bottom drain options, port sizes, and connection points to facilitate smooth integration. Our standard Productainer configurations are also designed to fit in-market outer plastic containers (drums and totes), simplifying integration. You can also use the Single-Use Assembly configurator to design the Productainer to your specifications.
Chamber geometry and port configuration play a critical role in process performance. The 3D chamber design enables uniform fluid distribution, while strategically placed drains ensure efficient, complete emptying. Optimized port size and placement support controlled transfer rates for both feeding and dispensing - minimizing hold-up and delivering consistent results across volumes and process steps.
Productainer systems are manufactured to the highest quality standards - produced under cGMP conditions in ISO 7 cleanrooms using qualified film materials. Gamma irradiation ensures sterility, while full lot traceability provides the transparency and control needed for compliance.
The result: reduced contamination risk and consistent, reliable performance you can trust across every batch and application.
Productainers are built to integrate effortlessly into your existing single-use systems. Compatible with industry-standard tubing, tri-clamp fittings, quick-connects, and aseptic connectors, they connect seamlessly across your process - from upstream bioreactors to downstream purification, storage, and transfer. The result is streamlined workflow alignment, faster setup, and efficient, reliable bioprocessing from end to end.
Selecting the right Productainer solution starts with understanding your process - required volumes, transfer steps, storage conditions, and facility constraints. Container footprint and compatibility with drums and totes are key to ensuring a seamless fit within your operation. Equally important are port and drain configurations, workflow integration, and film performance. Factor in sterility requirements and the need for customized tubing, connectors, or filters to support efficient, scalable, and compliant operations.
Explore related bioprocessing bags and containers
Complementary bioprocessing bags and containers support upstream and downstream liquid-handling steps—from buffer and media preparation to feed delivery, fraction collection, and bulk storage, helping create a seamless, closed workflow that improves efficiency, scalability, and process consistency. Explore other bioprocessing bags.
Design your single-use fluid transfer assembly—faster and with confidence
Our Single-Use Assembly Configurator Tool makes it easy to create custom assemblies tailored to your process or select in-stock, ready-to-ship options to help reduce lead times.
Additional bioprocessing resources
Bioprocessing resources
For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.