Search
On this page:
Standard single-use bottle assemblies for closed, sterile fluid transfer
Pre-assembled, gamma-irradiated bottle systems designed to streamline fluid handling, reduce contamination risk, and accelerate bioprocess workflows. Single-use bottle assemblies are ready-to-use fluid transfer systems that combine bottles, tubing, and closures into a sterile, closed solution—eliminating the need for in-house assembly, cleaning, and validation.
Benefits:
- Helps reduce contamination risk with closed systems
- Helps eliminate cleaning and validation steps
- Save time with ready-to-use assemblies
What are single-use bottle assemblies?
Single-use bottle assemblies are preconfigured, sterile systems used to transfer, store, and sample fluids in bioprocessing. They integrate bottles, tubing, and closures into a single, ready-to-use solution that reduces setup time and minimizes contamination risk.
Why are they used?
- Reduce contamination risk in fluid transfer
- Eliminate cleaning and sterilization requirements
- Improve efficiency and reduce labor time
Simplify fluid handling while reducing risk
Reduce operational burden
Eliminate the need to source components, assemble systems, and validate cleaning processes. Preconfigured assemblies arrive ready to use, helping teams focus on core process activities.
Improve process safety
Closed system designs help minimize exposure to the environment, reducing the risk of contamination and supporting consistent product quality.
Accelerate workflow
Gamma-irradiated and fully assembled, these systems reduce setup time and enable faster turnaround between batches.
Enable flexibility
Available in multiple sizes and configurations, bottle assemblies can be selected to meet a wide range of process requirements from sampling to bulk handling.
Applications across bioprocessing workflows
Designed to support both upstream and downstream operations, single-use bottle assemblies provide a flexible solution for fluid handling across development, pilot, and production environments.
- Media and buffer transfer
- Sampling during upstream processing
- Harvest collection and bulk storage
- Filtration and downstream connections
Standard bottle assembly configurations
Materials
Choose from durable, bioprocess-compatible materials including polycarbonate (PC) and PETG to meet your application needs.
Sizes
Available in volumes ranging from 125 mL to 2 L to support both small-scale sampling and larger fluid handling requirements.
Port options
Configurations include 2-port and 3-port designs, enabling flexibility for venting, transfer, and sampling operations.
Assembly components
Each assembly integrates a bottle, cap, tubing, and optional filters into a single, ready-to-use system.
Tubing
Includes C-Flex tubing designed for compatibility with sterile welding and sealing processes.
Sterility assurance
Manufactured and gamma-irradiated to achieve a sterility assurance level (SAL) of 10⁻⁶.
Connectivity
Compatible with common bioprocessing connection methods, including welding and sealing technologies.
Preconfigured vs. in-house assembly
| Factor | Single-use assemblies | In-house assembly |
Setup time |
Minimal setup required |
Time-intensive assembly |
Contamination risk |
Reduced with closed system |
Higher risk of exposure |
Validation |
No cleaning validation required |
Cleaning validation required |
Complexity |
Simplified procurement and use |
Multiple components and steps |
Designed for easy bioprocess integration
Single-use bottle assemblies are designed to integrate easily into existing bioprocess workflows. Their compatibility with sterile welding and sealing systems enables quality connections within closed processing environments.
These assemblies support scalability from research and development to full production, helping ensure consistent performance across process stages.
Ordering information
Related resource
Frequently asked questions
Bottle assemblies are used to transfer, store, and sample fluids in bioprocessing applications. Their closed, sterile design helps reduce contamination risk while simplifying fluid handling workflows.
Yes, assemblies are gamma-irradiated and manufactured to meet a sterility assurance level (SAL) of 10⁻⁶, ensuring they are ready for use in critical applications.
Assemblies typically include C-Flex tubing, which is compatible with sterile welding and sealing processes commonly used in bioprocessing.
Standard bottle assemblies are available in sizes ranging from 125 mL to 2 L, supporting a variety of applications from sampling to bulk fluid handling.
Additional bioprocessing resources
Bioprocessing resources
For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.