Orbitrap Exploris GC S MS Dioxin Analysis

Modernize dioxin analysis workflows with Orbitrap Exploris GC S

Dioxin analysis demands uncompromising sensitivity, selectivity, and data integrity at ultra-trace levels. To confidently meet regulatory requirements, even in the most complex food and environmental matrices, the Thermo Scientific Orbitrap Exploris GC S Mass Spectrometer combines high-resolution accurate-mass (HRAM) performance with exceptional robustness. Modernize dioxin analysis workflows and exceed analytical targets with regulatory-ready identification, increased scope, and streamlined workflows in an easy-to-use system.

What customers are saying about GC Orbitrap for dioxin analysis

"For routine EPA 1613 testing, reliability, robustness, and data robustness are critical. Transitioning to Orbitrap GC has enabled us to maintain the performance we expect from high-resolution systems, while gaining operational advantages such as simplified workflows, lower maintenance costs, and flexibility for future analytical needs, all of which better support our long-term sustainability as a contract testing laboratory."

Dr. Karl Mair
Eco Center s.p.a, Bolzano, Italy

Simplify the complexity of dioxin analysis

Implement routine dioxin analysis quickly with an integrated, compliance-ready workflow. For a guided, end-to-end solution that automates method setup, quality checks, data processing, and reporting, the Chromeleon dioxin HRAM eWorkflow combines Orbitrap Exploris GC S and Thermo Scientific Chromeleon Software, allowing laboratories to be operational with minimal manual configuration.

Chromeleon dioxin HRAM eWorkflow

Chromeleon dioxin HRAM eWorkflow provides real-time compliance monitoring through dynamic, color-coded indicators for internal standard recovery, ion ratios, and TEQ calculations, while built-in system suitability checks ensure only compliant sequences proceed. Preconfigured reporting templates automatically generate complete, regulation-ready documentation—from ¹³C-labeled standard recoveries to LOQ flagging—simplifying data review, reducing operator burden, and ensuring consistent results across routine high-throughput analysis.

Injection parameters

GC gradient

HRAM acquisition

Data processing & reporting

Splitless (SSL)
Programmable temperature vaporisation (PTV)

GC oven temperature program
Dioxin column options

SIM HRAM acquisition
Orbitrap Exploris GC or GC S

Pre-installed/customizable templates for dioxin
Sequence setup, data evaluation & reporting

Regulatory-ready performance

Deliver results with confidence. Orbitrap Exploris GC S can help you meet the demanding performance expectations of regulated dioxin workflows so you can be ready for method requirements from day one. The information and data that follows demonstrates how the system meets the technical demands of dioxin regulations.

Sensitivity and repeatability at ultra-trace level

Chromeleon integrated peaks for eight QC replicates over ~180 injections (10 fg on-column 2,3,7,8-TCDD in solvent).

Line plot of response across ~180 injections for eight QC replicates (10 fg on-column 2,3,7,8-TCDD in solvent).

Exceed mass resolution targets

Chromeleon report view of m/z resolution at 5% peak height (columns right side) for all congeners in CSL (calibration solution lowest) and CS4 (calibration solution 4) exceeds regulation target of 10,000 with all at ~20,000.

Ion ratio performance at trace level

Chromeleon report view of ion ratio (right side) showing all congeners at <15% at 15 fg on column in soil matrix over 10 replicate injections. Chromeleon automatically calculates and flags the ion ratio confirmation to user. All relative standard deviation (%) of the 10 replicates in soil matrix < 7%.