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Label-Free Quantitation Resources

Resources

Access our library of brochures, technical notes, and case studies to learn more about the label-free quantitation workflow.

Quantitative proteomics brochure

A brochure detailing our solutions for various quantitative proteomics techniques.

Review of modern techniques in quantitative proteomics

A technical review for biologists, comparing MS workflows, labeling strategies, and considerations for high-throughput quantitative proteomics.

Single-Cell Proteomics on an Orbitrap Astral Zoom mass spectrometer

Learn about the performance of the Orbitrap Astral Zoom MS for single-cell proteomics and low input samples.

LFQ workflow on an Orbitrap Ascend MultiOmics mass spectrometer

Learn about the performance of LFQ, workflow on an Orbitrap Ascend MultiOmics MS.

LFQ workflow on an Orbitrap Exploris 480 mass spectrometer

Learn about the performance of LFQ workflow on Orbitrap Exploris 480 MS.

High-throughput quantitative proteomics with Evosep Eno and the Orbitrap Astral Zoom mass spectrometer

Learn how ultra-high-throughput nDIA proteomics achieves deep, reproducible quantitation across hundreds of daily samples.

High coverage and accuracy in quantitative proteomics using the OptiSpray ion source on the Orbitrap Excedion Pro mass spectrometer

Learn how DIA-LFQ workflows improve proteome coverage, quantitation accuracy, and reproducibility using advanced MS technologies.

Label-free quantitation with high accuracy and precision using the Orbitrap Excedion mass spectrometer

Learn how accurate DIA-based label-free quantitation enables deep, scalable proteome coverage across diverse sample conditions.

Scalable and robust DIA proteomics with flexible throughput on the Orbitrap Excedion Mass Spectrometer

Learn how flexible DIA workflows preserve proteome depth, reproducibility, and sensitivity across diverse sample conditions.

For Research Use Only. Not for use in diagnostic procedures.

General Laboratory Equipment – Not For Diagnostic Procedures. © 2026 Thermo Fisher Scientific Inc. All rights reserved. Thermo Scientific™ products are designated as General Laboratory Equipment and are not intended for use in diagnostic procedures or for in vitro diagnostic purposes. These products are intended for general laboratory use only and have not been tested or validated for diagnostic applications; use for such purposes may result in inaccurate results and may pose health and safety risks. They are designed for research, academic, and industrial applications and for general-purpose analytical use, including high-resolution and accurate-mass measurements, without reference to specific clinical conditions, analytes, or diagnostic decisions.

The Thermo Scientific Orbitrap Exploris and Excedion series mass spectrometers are Orbitrap instruments with an atmospheric pressure ionization (API) source for liquid chromatography (LC) mass spectrometry (MS) high-throughput applications. The instruments are designed to be placed on a bench in the laboratory and maintain mass accuracy across chromatographic peaks, supporting confident identification and quantitation using high-resolution accurate-mass detection.