DXR3 SmartRaman+ Spectrometer

Fast, non-destructive, at-line testing for rapid batch release

The Thermo Scientific DXR3 SmartRaman+ Spectrometer was developed in close collaboration with manufacturers to provide the sampling flexibility, connectivity and efficiency that industry demands. Built on the renowned DXR platform from Thermo Fisher Scientific, the DXR3 SmartRaman+ Spectrometer adds a new level of precise, at-line, semi-automated testing to the dependable performance the DXR3 platform is already known for.

Applications

Pharmaceutical manufacturing: Fill-and-finish testing 

The DXR3 SmartRaman+ Spectrometer enables efficient and accurate quality control via non-destructive analysis, with high throughput rates that can shorten batch release testing from weeks to mere hours.

  • Raman technology can perform non-destructive measurement through a wide range of finished packaging, so there is no threat to the integrity of products.
  • Automatic batch testing reduces operators’ work time and generates results faster.
  • High-resolution performance allows for detection of low concentrations of analytes.
  • Industry-standard OPC UA connectivity allows for seamless integration into the current manufacturing environment.

Industrial quality control testing

The DXR3 SmartRaman+ Spectrometer enhances industrial product quality testing by enabling rapid, high-throughput quality checks. Sampling flexibility is aided by custom sample holders. With its intuitive design, the instrument eliminates the need for Raman expertise, delivering seamless integration into industrial quality control operations.

 

Research and method development

The DXR3 SmartRaman+ Spectrometer is perfect for research and method development. Its versatile design supports multiple applications, featuring user-exchangeable lasers and the ability to acquire spectral data with higher resolution than required for pharmaceutical testing. It enables precise analysis of a wide range of diverse samples, enhancing the effectiveness of R&D efforts.

Capabilities

High throughput

Elevate your pharmaceutical manufacturing process with the DXR3 SmartRaman+ Spectrometer by helping to ensure your products meet your specifications. Featuring at-line auto-sampling and high-throughput analysis, the DXR3 SmartRaman+ Spectrometer significantly enhances operational efficiency during the critical fill-and-finish stage. Delivering rapid, accurate quality control feedback, the instrument shortens production time, reduces labor costs, and safeguards the highest standards of precision and reliability.

Sampling flexibility

The DXR3 SmartRaman+ Spectrometer offers exceptional sampling flexibility supporting user-designed custom multi-sample holders that accommodate a wide range of container shapes and sizes, including vials, cuvettes, well plates, and bottles. This means that the DXR3 SmartRaman+ Spectrometer can be employed to perform non-destructive testing directly through the most commonly used product containers, preserving sample integrity without the need for instrument modification. Additionally, the autosampler is also factory-calibrated to provide for inter-autosampler positional reproducibility. This increased versatility enhances testing capabilities, while the trusted DXR3 backbone maintains a high standard of accuracy and efficiency.

USP and Ph.Eur. validations

Help ensure your pharmaceutical processes meet high industry standards with the DXR3 SmartRaman+ Spectrometer. Fully qualified to comply with USP and Ph.Eur. quality standards, this spectrometer allows you to perform essential qualification tests as part of your routine validation and maintenance procedures. Maintain consistent adherence to industry regulations and help ensure a high level of quality in your operations.

 

Reduce sample wastage

The DXR3 SmartRaman+ Spectrometer helps preserve valuable resources by utilizing non-destructive Raman spectroscopy to help ensure sample integrity and eliminate waste. This advanced technique maintains the original state of your samples and delivers accurate results without requiring any consumption or disposal of tested product. 

 

Measure through containers and packaging

Achieve efficient and precise quality control with the DXR3 SmartRaman+ Spectrometer, which facilitates non-destructive measurement directly through vials, containers, and several other forms of packaging. This advanced capability helps ensure the integrity of your samples is maintained, eliminating the need for sample preparation and streamlining your testing processes.

Features

User-exchangeable lasers

The DXR3 SmartRaman+ Spectrometer delivers exceptional versatility by supporting user-exchangeable 532nm and 785nm lasers. This flexibility allows for precise analysis of a wide variety of sample types, including highly fluorescent materials. Whether for quality control deployment or method development, the DXR3 SmartRaman+ spectrometer adapts to diverse samples and application.

Ease of use

Simplify your quality control process with the DXR3 SmartRaman+ Spectrometer, which features user-friendly hardware and requires minimal interaction with software. Designed to reduce the need for expert users and minimize training time, its intuitive design and automated software operations help ensure quick adoption and efficient use in manufacturing environment. The easy-to-use DXR3 SmartRaman+ Spectrometer will help you streamline your operations and enhance productivity.

Research-grade data

The DXR3 SmartRaman+ Spectrometer delivers research-grade data without compromising on spectral resolution, accuracy or the users’ ability to select common excitation wavelengths of 532 nm and 785 nm. Built on the DXR3 platform that has been trusted by experts for over a decade, the DXR3 SmartRaman+ Spectrometer features robust optical, electronic, and mechanical assemblies to power your work with reliable and precise results.

 

Industry-standard OPC UA connectivity

Integrate your analytical process seamlessly into your manufacturing environment with the connectivity features of the DXR3 SmartRaman+ Spectrometer. Featuring Open Platform Communications with Unified Architecture (OPC UA), which is recommended for Industry 4.0 connectivity, the DXR3 SmartRaman+ Spectrometer makes communication between your instruments simple. Because OPC UA allows central servers to exchange commands and data with instruments from different makers easily, it is advancing globally as an interoperability standard, facilitating manufacturing and digital transformation (DX). With advanced connectivity at its core, the DXR3 SmartRaman+ Spectrometer is designed for you to maximize your operational efficiency as you advance into the future.

 

While the local software offers basic measurement and experimental setup capabilities, the instrument is primarily designed for operation through a local or remote server using OPC UA control, making it ideal for manufacturing environments.

 

Worldwide service and support

Maximize productivity and optimize performance with Thermo Fisher Scientific’s comprehensive service plans, designed to support your DXR3 SmartRaman+ Spectrometer throughout its entire lifecycle. Our global Product and Applications Support program keeps your operations productive and running seamlessly—wherever you are.

 

Exclusive service advantages:

  • On-site training: Empower your team with hands-on, expert training tailored to your specific needs.
  • Unlimited technical support: Access our dedicated technical support team anytime, ensuring you always have the help you need.
  • Extended warranties: Enjoy peace of mind with extended coverage for your spectrometer.
  • Parts-only warranties: Protect your investment with warranties that cover essential parts.
  • System compliance: Maintain compliance with industry standards effortlessly. Speak with your sales representative today to discover how our service and support options can elevate your lab’s performance and productivity.

For Research Use Only. Not for use in diagnostic procedures.