What is an automated laboratory incubator?

An automated incubator is a robotic-accessible laboratory system designed to store, incubate, and manage microplates or labware under controlled environmental conditions. Automated cell culture incubators provide precise temperature, humidity, and CO₂ regulation while enabling seamless integration with robotic movers and lab workflow software. From shaking incubators to high-capacity plate storage systems, automated lab incubators support scalable, high-throughput laboratory automation environments.

Shake, spin, or store your samples with confidence

Laboratory equipment manufacturers and researchers globally rely on the highly dependable Thermo Scientific Cytomat automated incubators and microplate storage systems. With over 50 years of expertise in CO2 incubator technology, the robot-accessible Cytomat series stands as the industry leader. Ensure a substantial boost in productivity and efficiency by properly storing and accessing your valuable samples.


Key features of Thermo Scientific Cytomat automated incubators


Model selection guide for Cytomat incubators

Choose from a wide range of Cytomat series models to match your cell culture application requirements.

Explore how automated incubators support laboratory automation applications in drug discovery, biologics development, and genomics.

 

Our automation experts can help you match the right Cytomat Automated Incubator configuration to your workflow, capacity, and environmental requirements.

Low temperature range incubation & storage

Low temperature storage (from 4°C up to 25°C) provided in various capacities.

 

The Thermo Scientific Cytomat Automated Incubator & Storage Series offers robot-compatible random-access storage for up to 504 standard microplates, seamlessly integrating into any automated system for diverse applications. This series supports a wide range of temperatures (4°C to 25°C), humidity levels, and gaseous atmospheres.

View low temperature model specifications:

 

Model

Cytomat 2 C425-LiN Automated Incubator

Cytomat 5 C425 Automated Incubator

Cytomat 10 C425 Automated Incubator

Cytomat 24 C425 cH Automated Incubator

Number of stackers

2

5

10

24

Microplate capacity (based on a microplate height of 18mm)

42

105

210

504

True orbital shaking option

Available

Not available

Not available

Not available

Temperature range

4°C to 25°C

Humidity

Up to 90% r.H. @ 20°C

Up to 90% r.H. @ 20°C

Up to 90% r.H. @ 20°C

<5% up to maximum 30% r.H. @ 10°C

Controlled humidity with external water tank option

Available, customized  

Included as standard

Included as standard

Available

CO2

No

Fully automated de-contamination routine

Yes

Yes

Yes

No

Solid copper chambers

Optional (Stainless steel chamber as standard)

Optional (Stainless steel chamber as standard)

Optional (Stainless steel chamber as standard)

No

Bench placement

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Floor model

Mean access time

12 seconds

Below 10 seconds

Below 10 seconds

15 seconds

Plate park positioning (P³) sensor

Optional

Included as standard

Included as standard

Included as standard

Available options

  • 1D Barcode reader
  • Various stacker pitch sizes for different plate heights
  • Customized stackers for different labware
  • HydraSmart plus: Humidity control ≤ 10% rH at 10°C for dry environment
  • O2 control (1-21% or 5-90%) (Not available for Cytomat 24 C425 cH)
  • Door Left hinges (DL)
  • Connection flanges 1" in glass door for connection of an H2O2 generator for sterilization
  • Various gate options
  • Voltage 100V / 120V / 230V

Wide temperature range incubation and storage

Ideal environment for storage and incubation of your assays in a temperature range from 4°C up to 50°C (optional 70°C) with multiple capacities.

 

The Thermo Scientific Cytomat Wide Range Series provides robot-friendly random-access storage of up to 504 standard microplates and can be easily integrated into any automated system for multiple applications. This series is designed to accommodate a broad range of temperatures, humidity levels, and gaseous environments. It also includes CO2 control with every model.

Compare wide range automated CO₂ incubator models:

 

Model

Cytomat 2 C450-LiN Automated Incubator

Cytomat 5 C450 Automated Incubator

Cytomat 10 C450 Automated Incubator

Cytomat 24 C450 Automated Incubator

Number of stackers

2

5

10

24

Microplate capacity

42

105

210

504

Temperature range

4°C to 50°C (up to 70°C optional)

Humidity

Up to 95% r.H. at 37°C

Controlled humidity with external water tank

Optional

Yes

Yes

Optional

CO2 (comes as standard)

0-20 Vol. % (temp range 25 to 50°C)

Fully automated de-contamination routine

Yes

Solid copper chambers

Optional (Stainless steel chambers included as standard)

Bench placement

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Suitable for floor

Mean access time

12 seconds

Below 10 seconds

Below 10 seconds

15 seconds

Plate park positioning (P³) Sensor

Optional

Comes as standard

Comes as standard

Comes as standard

Available options

  • 1D Barcode reader
  • Various stacker pitch sizes for different plate heights
  • Customized stackers for different labware
  • HydraSmart plus: Humidity control ≤ 10% rH at 10°C for dry environment
  • O2 control (1-21% or 5-90%)
  • Door Left hinges (DL)
  • Connection flanges 1" in glass door for connection of an H2O2 generator for sterilization
  • Various gate options
  • Voltage 100V / 120V / 230V

 


37°C incubation and storage

The right choice for your application at 37°C up to 50°C (optional 70°C) in many capacities.

 

Achieve extremely uniform environmental conditions for all microplates, elimination of recovery times, and reduced assay variance. The Thermo Scientific Cytomat Incubation Series provides robot-friendly random-access storage of up to 504 standard microplates, are multi voltage (100-230V), and can be easily integrated into any automated system. The series supplies an ideal environment for storage and incubation of assays from room temperature +10°C up to 70°C (model dependent), with high humidity up to 95% r.H. and stable CO2 conditions.

See 37°C automated CO2 incubator configurations:

 

Model

Cytomat 2 C-LiN Automated Incubator

Cytomat 5 C Automated Incubator

Cytomat 10 C Automated Incubator

Cytomat 24 C Automated Incubator

Number of stackers

2

5

10

24

Microplate capacity

42

105

210

504

Temperature range

Room temperature +10°C - 50°C (up to 70°C optional)

Humidity

Up to 95% r.H. @ 37°C

Controlled humidity with external water tank

Optional

Yes

Yes

Optional

CO2 (comes standard)

0-20 Vol. % (temp range 25 to 50°C)

Fully automated de-contamination routine Yes

Solid copper chambers

Optional (stainless steep chambers included as standard)

Bench placement

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Floor model

Mean access time

12 seconds

Below 10 seconds

Below 10 seconds

15 seconds

Plate park positioning (P³) Sensor

Optional

Comes as standard

Comes as standard

Comes as standard

Available options

  • 1D Barcode reader
  • Various gate options
  • Various stacker pitch sizes for different plate heights
  • Customized stackers for different labware
  • HydraSmart plus: Humidity control ≤ 10% rH for dry environment
  • O2 control (1-21% or 5-90%)
  • hH – high humidity up to 98% rH at 37 °C (Note: condensation will occur)
  • Door Left hinges (DL)
  • Connection flanges 1" in glass door for connection of an H2O2 generator for sterilization

Ambient storage

Robot-friendly ambient storage in a wide capacity range for all applications.

 

Designed for easy integration into automated systems.

 

Thermo Scientific Cytomat Random Access Storage Hotels are designed to integrate into any automated system. From benchtop to floor standing models, Cytomat Hotels can accommodate from 42 to 504 shallow well plates, while the integrated plate shuttle system (PSS) can handle all SBS standard microplate formats, including deep-well plates and tip boxes. The system can also be customized for petri dish or protein crystallography applications. In addition, a high-capacity sequential plate storage device is available.

Explore the ambient storage options:

 

 

Model

Cytomat 2 C-LiN Hotel

Cytomat 10 Hotel  

Cytomat 24 Hotel

Cytomat SkyLine Automated Plate Storage and Delivery System

Number of stackers

2

10

24

14

Microplate capacity

42

210

504

728 (capacity dependent on plate height)

Storage design

Random access storage

Random access storage

Random access storage

Sequential loading/unloading

Temperature range

18°C - 30°C / Ambient

Bench placement

Suitable for benchtop or under bench

Suitable for benchtop or under bench

Floor model

Suitable for benchtop or under bench

Mean access time

12 seconds

Below 10 seconds

15 seconds

15 seconds

Plate park positioning (P³) sensor

Optional

Comes as standard

Comes as standard

N/A

Available options

  • Various transfer position options
  • 1D Barcode reader
  • Various stacker pitch sizes for different plate heights
  • Customized stackers for different labware

 


Automated shaking incubators and shaker incubator systems

Providing true-orbital shaking for applications requiring sample agitation.

 

The Thermo Scientific Cytomat Automated Incubators offer advanced shaking solutions for biotherapeutic workflows. The Cytomat 2 Selector and Cytomat 2 Tower Shaker provide secure and consistent amplitude shaking capabilities, ensuring reproducible results and reducing contamination risk. The Cytomat 2 Selector features a 25 mm shaking diameter with speeds from 100 to 350 rpm, ideal for biologics. The Cytomat 2 Tower Shaker sets a new standard with its synchronized dual magnetic drive system, offering precise sample agitation for cells in suspension and secure plate and lid clamping. Both models support a wide range of applications, including cell culture, microbial culture, genomics, biotherapeutics discovery and synthetic biology, making them perfect for drug discovery and life science research.

Explore shaking incubator capabilities:

 

Model

Cytomat 2 Selector Automated Shaking Incubator

Cytomat 2 C450-LiN ToS

Number of stackers

2

Microplate capacity

16:
16 plates (for up to 52mm plate height; Pitch 57)

 

8 plates (for up to 110mm; Pitch 115)

 

32:

32 plates (for up to 18mm; Pitch 23 )

14 plates (for up to 47mm; Pitch 52)

 

12 plates (for up to 55mm; Pitch 60).

 

Other plate height stacker on request.

True Orbital Shaking

Yes

Shaking diameter

25mm

2mm or 3mm

Shaking speed

100 - 350 rpm

300 – 1200 rpm

Temperature range

15°C to 50°C

10°C to 50°C

Humidity

Up to 85% r.H.

Up to 80% r.H.

CO2 (Comes as standard)

0-20 Vol. % (temp range 25 to 50°C)

Fully automated de-contamination routine

Yes

Solid copper chamber material

Stainless steel

Bench placement

Suitable for benchtop or under bench

Available options

  • 1D Barcode reader
  • P3 -plate detection in stacker
  • O2 control (1-21% or 5-90%)
  • Door Left hinges (DL)
  • H2O2 disinfection ports (GDF)
  • Air Purging System (APS) - CO2 reduction during cell growth down to 1%
  • Various gate options
  • Various Tower Shaker stacker pitch sizes for different plate heights

 

From automated CO₂ incubators to shaking and ambient storage systems, Thermo Scientific Cytomat solutions integrate with robotics and lab automation software to enable total lab automation.

For Research Use Only. Not for use in diagnostic procedures.