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Gibco
Human APRIL Recombinant Protein, PeproTech®
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产品信息
310-10C-1MG
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Mouse
Expression System
Insect cells
分类
Recombinant
类型
Protein
偶联物
形式
Lyophilized
保存条件
-20°C
运输条件
Ambient
产品详细信息
310-10C-01M will be provided as 20 x 50 µg (310-10C-50UG).
310-10C-500 will be provided as 10 x 50 µg (310-10C-50UG).
310-10C-250 will be provided as 5 x 50 µg (310-10C-50UG).
310-10C-100 will be provided as 2 x 50 µg (310-10C-50UG)
Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues. *Human APRIL (Catalog Number 310-10C) has replaced Human APRIL (Catalog Number 310-10).
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
