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Invitrogen
Human CASK (aa 578-592) Synthetic Peptide
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产品信息
PEP-110
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PEP-110 is a 15 amino acid synthetic peptide whose sequence corresponds to amino acid residues 578-592 of human CASK. The sequence of this peptide is (amino to carboxy terminus): C (578)-E-R-D-S-P-S-T-S-R-Q-S-P-A-N (592)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human CASK, catalog # PA1-544. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member. CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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