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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CDCP1 is a transmembrane protein containing three extracellular CUB domains. It is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. CDCP1 is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CDCP1; gp140; gp140/p80/CDCP1; membrane glycoprotein gp140; novel cell surface glycoprotein 135 kDa; subtractive immunization M plus HEp3-associated 135 kDa protein; transmembrane and associated with src kinases; unnamed protein product
基因别名: CD318; SIMA135; TRASK
UniProt ID: (Human) Q9H5V8
Entrez Gene ID: (Human) 64866