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Invitrogen
Human DEPDC6 (aa 139-206) Control Fragment Recombinant Protein
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产品信息
RP-93837
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
LYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEAEQLCHRLMEHGIIQHVSNKH
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82857. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
DEPDC6 is a gene that encodes a protein known for its role in various cellular processes, although the specifics of its function remain not fully elucidated. Located on chromosome 22, DEPDC6 is involved in regulating cell growth and survival by modulating the RAS signaling pathway, a crucial pathway for many cellular functions. Structurally, DEPDC6 contains a DEP domain, which is known to mediate interactions with other proteins that are involved in signal transduction. This domain plays a significant role in facilitating the proper localization and function of the protein. Functionally, DEPDC6 is implicated in controlling the pathways that govern the timing and progression of the cell cycle, highlighting its importance in maintaining cellular homeostasis and preventing uncontrolled cell proliferation. Its dysregulation has been associated with various cancers, emphasizing the need for further studies to fully understand its potential as a therapeutic target.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DEP domain containing 6; DEP domain containing mTOR interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; hDEPTOR
基因别名: DEP.6; DEPDC6; DEPTOR
UniProt ID: (Human) Q8TB45
Entrez Gene ID: (Human) 64798
