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PEP-136 is a 15 amino acid synthetic peptide whose sequence corresponds to amino acid residues 171-185 from human Dnmt1 protein. The sequence of this peptide is (amino to carboxy terminus): A (171)-K-G-P-A-K-R-K-P-Q-E-E-S-E (185).
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human Dnmt1 protein, catalog # PA1-880. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。