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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111385. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAE2; ECA2; GABA(A) receptor subunit gamma-3; GABA(G) receptor; GABA(G) receptor, gamma 3; GABAAR subunit gamma-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 3; Gamma-aminobutyric acid receptor subunit gamma-3; GEFSP3
基因别名: GABRG3
UniProt ID: (Human) Q99928
Entrez Gene ID: (Human) 2567