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Invitrogen
Human GNG5 (aa 31-67) Control Fragment Recombinant Protein
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产品信息
RP-99261
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
AAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVCSF
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60452. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327];Summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: guanine nucleotide binding protein (G protein), gamma 5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
基因别名: GNG5; GNGT5
UniProt ID: (Human) P63218
Entrez Gene ID: (Human) 2787
