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Invitrogen
Human Galectin 14 Control Fragment Recombinant Protein
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产品信息
RP-109081
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
QFRLHFGHPAIMNSRVFGIWRYEEKCYYLPFEDGKPF
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139873. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Galectin-14 is a member of the galectin family of proteins, which are characterized by their affinity for beta-galactoside sugars and involvement in various biological processes including cell-cell adhesion, immune response modulation, and apoptosis. The gene encoding Galectin-14, LGALS14, is located on chromosome 19q13.2. Galectin-14 is predominantly expressed in eosinophils and has been identified to play a role in allergic response and inflammation. It is known to participate in the modulation of immune responses, particularly asthma and other allergic conditions, by interacting with glycoproteins on cell surfaces. The expression of Galectin-14 is elevated during allergic reactions and this molecule is considered a potential biomarker for eosinophilic activity in such conditions. There is ongoing research into the exact mechanisms of Galectin-14 in immune response modulation, which might provide insights into novel therapeutic approaches for managing allergic diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charcot-Leyden crystal protein 2; CLC2; Gal-14; Galectin-14; lectin, galactoside binding soluble 14; lectin, galactoside-binding, soluble, 14; MGC22235; Placental protein 13-like; placental protein 13-like protein
基因别名: CLC2; LGALS14; PPL13
UniProt ID: (Human) Q8TCE9
Entrez Gene ID: (Human) 56891
