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Invitrogen
Human HSD17B3 Control Fragment Recombinant Protein
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产品信息
RP-103273
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
NVGILPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLIL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63356. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; Estradiol 17-beta-dehydrogenase 2; HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_1; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_2; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_4; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_5; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
基因别名: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058
Entrez Gene ID: (Human) 3293
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