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Gibco
Human IL-18 Recombinant Protein
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产品信息
PHC0186
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human IL-18, amino acids 37-193
分子量
18 kDa
分类
Recombinant
类型
Protein
纯度
>90% by SDS-PAGE
内毒素浓度
<0.1 ng/µg
活性
Determined by the dose-dependent production of IFN-gamma by human KG-1 myelomonocyte cells.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS with 0.1% BSA, 1% sucrose
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Reconstitution: We recommend the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute with 250 µL ice cold, sterile, distilled water on ice.
Storage: Store this lyophilized preparation at -20°C, preferably desiccated. Upon reconstitution, the protein may be stored at 2°C to 8°C for up to one week. For long term storage of the reconstituted protein, apportion into working aliquots and store at -80°C. Avoid repeated freeze/thaw cycles.
靶标信息
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Iboctadekin; IFN-gamma-inducing factor; il 18; IL-1 gamma; IL-18; ILN; Interferon gamma-inducing factor; Interleukin; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; Interleukin-18; Interleukin18; MGC12320
基因别名: IGIF; IL-18; IL-1g; IL18; IL1F4
UniProt ID: (Human) Q14116
Entrez Gene ID: (Human) 3606
