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Highest antigen sequence indentity to the following orthologs: Mouse (30%), Rat (30%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52082. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 7.1; cancer/testis antigen family 7, member 1; CT7.1; MAGE-C1 antigen; melanoma antigen family C, 1; melanoma antigen family C1; Melanoma-associated antigen C1
基因别名: CT7; CT7.1; MAGEC1
UniProt ID: (Human) O60732
Entrez Gene ID: (Human) 9947