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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66290. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin (PubMed:28167679, PubMed:22628566). Plays a role in sister chromatid cohesion and normal progression through prometaphase (PubMed:16802858, PubMed:16682347). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cohesin loading complex subunit SCC4 homolog; MAU-2; MAU2 chromatid cohesion factor homolog; MAU2, sister chromatid cohesion factor; protein MAU-2; sister chromatid cohesion 4
基因别名: KIAA0892; mau-2; MAU2; MAU2L; SCC4
UniProt ID: (Human) Q9Y6X3
Entrez Gene ID: (Human) 23383