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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67454. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial 18 kDa protein; Mitochondrial fission process protein 1; mitochondrial fission protein MTP18; mitochondrial protein 18 kDa; MTP18
基因别名: HSPC242; MTFP1; MTP18; My022
UniProt ID: (Human) Q9UDX5
Entrez Gene ID: (Human) 51537