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Invitrogen
Human MYO3A (aa 1522-1600) Control Fragment Recombinant Protein
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产品信息
RP-106356
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
KRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRERRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140174. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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