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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63823. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Drosophila retinal degeneration B homolog; FLJ44997; Membrane-associated phosphatidylinositol transfer protein 1; NIR-2; phosphatidylinositol transfer protein, membrane associated 1; Phosphatidylinositol transfer protein, membrane-associated 1; PITPnm 1; PYK2 N-terminal domain-interacting receptor 2; retinal degeneration B alpha 1
基因别名: DRES9; NIR2; PITPNM; PITPNM1; Rd9; RDGB; RDGB1; RDGBA; RDGBA1
UniProt ID: (Human) O00562
Entrez Gene ID: (Human) 9600