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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53684. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: common-site lymphoma/leukemia guanine nucleotide exchange factor; CTB-60E11.4; DKFZp667J2325; FLJ00018; FLJ22458; FLJ38638; PH domain-containing family G member 2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; Pleckstrin homology domain-containing family G member 2
基因别名: ARHGEF42; CLG; LDAMD; PLEKHG2
UniProt ID: (Human) Q9H7P9
Entrez Gene ID: (Human) 64857