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Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59217. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Pix2; POC1 centriolar protein homolog A; Proteome of centriole protein 1A; WD repeat domain 51A; WD repeat-containing protein 51A
基因别名: PIX2; POC1A; SOFT; WDR51A
UniProt ID: (Human) Q8NBT0
Entrez Gene ID: (Human) 25886