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Invitrogen
Human STEAP3 (aa 61-127) Control Fragment Recombinant Protein
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产品信息
RP-101206
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
PKRTARLFPSAAQVTFQEEAVSSPEVIFVAVFREHYSSLCSLSDQLAGKILVDVSNPTEQEHLQHRE
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62202. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dudlin 2; Dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Six-transmembrane epithelial antigen of prostate 3; STEAP family member 3, metalloreductase; tumor suppressor pHyde; Tumor suppressor-activated pathway protein 6
基因别名: AHMIO2; dudlin-2; dudulin-2; pHyde; STEAP3; STMP3; TSAP6
UniProt ID: (Human) Q658P3
Entrez Gene ID: (Human) 55240
