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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63974. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial protein with oncostatic activity; Mitostatin; Protein TCHP; TCHP; Trichoplein keratin filament-binding protein; trichoplein, keratin filament binding; Tumor suppressor protein
基因别名: TCHP; TpMs
UniProt ID: (Human) Q9BT92
Entrez Gene ID: (Human) 84260